Sometimes a NoScript user will report problems like missing icons/menus, broken permissions and so on. That never happens to most users, but if you run across a problem like this, update NoScript to the most recent development build at http://noscript.net/getit#devel and try these steps, in order, until NoScript is working right again.
1) If you have any Firefox extensions called HP Smart Web Printing, Skype, .NET Framework Assistant, or McAfee Site Advisor, then uninstall or disable them. They're buggy and known to cause problems with the status bar icon.
2) If you are having a particularly odd issue with NoScript not functioning properly, or you are seeing the same domain(s) in the menu on every site, scan your system for malware. Here are some suggestions:
Windows users: use both your antivirus and a tool like Malwarebytes Anti-Malware (the free version will do); if that doesn't get it, try yet another type of malware scanner, e.g. AdwCleaner and/or Junk Removal Tool. Daifne @ mozillaZine forums also has some good suggestions.
Mac users: try ClamXav.
Linux/*BSD users: try ClamAV (which should be available via your OS's package manager).
Disclaimer: Neither InformAction Forums nor anyone on forum staff is in control of these programs, and they are not endorsed by InformAction Forums. We cannot take responsibility for what they do or how well they work. Use at your own risk.
3) The NoScript settings became messed up somehow. Reset the NoScript Options by pressing Reset at the bottom of the Options dialog. Export your whitelist before doing that if you've added any trusted or untrusted sites you'd like to restore after NoScript is working again.
4) The extensions database is corrupted. Exit Firefox, delete the files mentioned here in this linked article, restart Firefox. Uncorrupted versions of the files will be automatically regenerated. Corrupt_extension_files
5) There might be an extension conflict. Use the Add-ons manager to temporarily disable any other Firefox extensions you have installed except for NoScript.
6) Perform a Standard Diagnostic. If NoScript isn't working by the time you get to the "Create a new profile" step, a new profile with no other extensions besides NoScript should work right.