I believe you learn how to use NS in less than couple of minutes, if you stop complaining and forget what and how NS 5 did. And start learning with clean install.
This problem sounds and surely is that old NS settings were corrupted before or during uppgrading from 5 to 10. I think that this process is not very good handled by NS.
But nevertheless, NS 10 is much better and easier and more effective than 5 now when those handicaps of first versions are fixed.
About the first sentence you wrote. I would agree with it if you had said, that if you knew how to use NoScript 5, learning NoScript 10 would take a couple of minutes.
But according to what the opening poster wrote, it doesnt sound to me like he used NoScript before. He sounds like a first time NoScript user. And one who expected NoScript to make websites work magically. And thats not how NS works. It has to be learned via trial and error, and it takes a lot of time. In my personal case, it took me about 2 years to move from what I consider a basic Temporarily allow all this page user to become an advanced user.
I have been using NoScript for 9 years. During all this years, I read many times complains that sound pretty much identical to his. When I read one like that, I always try to tell who wrote it that learning NoScript is not easy but it is worth learning. The learning process takes awhile. But once you learn it, is like learning to ride a bicycle, you just keep going. Once NoScript does click in your head, you are pretty much done. When I first started using NoScript, I took a no nonsense approach to it and went with it. And then one day all things started making sense. Never got frustrated or uninstalled NoScript.
So, his problem is not because Settings got corrupted (IMO, and according to what he wrote).
If you know how to use NoScript, and your settings got corrupted, you ll know immediately that something is not right. i have 2 computers right now, in both I waited for NoScript 10 to be released before updating to Firefox 57. In my W10, settings were corrupted during the update. For me, it was easy to fix. I copied my settings from my W7 and replaced the ones in W10, and that did it.
I also like version 10. I cant find anything wrong with it.